Dopamine anatomy
نویسندگان
چکیده
منابع مشابه
The anatomy of choice: dopamine and decision-making
This paper considers goal-directed decision-making in terms of embodied or active inference. We associate bounded rationality with approximate Bayesian inference that optimizes a free energy bound on model evidence. Several constructs such as expected utility, exploration or novelty bonuses, softmax choice rules and optimism bias emerge as natural consequences of free energy minimization. Previ...
متن کاملDopamine Receptor Diversity: Anatomy, Function, and Relevance to Parkinson’s Disease
The importance of dopamine in the motor functions of the striatum is evident in Parkinson’s disease (PD). The striatum controls motor activity by processing the flow of information arising from the cerebral cortex and projecting via direct and indirect pathways to the output nuclei of the basal ganglia. The degenerative loss of dopamine is a hallmark of this disease and leads to severe motor im...
متن کاملMolecular anatomy of neuronal interactions with special reference to the dopamine control of striatal functions.
Modern neuroanatomy was initiated at the early beginning of the XX century when Cajal used the so-called silver impregnation technique to study the details of the anatomy of the nervous system. This technique, for the first time, permitted description and visualization of all components of neurons (Cajal, 1909). Thanks to this major methodological advance, Cajal and followers created microscopi...
متن کاملImaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy
[(11)C]-(+)-PHNO is a D3 preferring PET radioligand which has recently opened the possibility of imaging D3 receptors in the human brain in vivo. This imaging tool allows characterisation of the distribution of D3 receptors in vivo and further investigation of their functional role. The specific [(11)C]-(+)-PHNO signal is a mixture of D3 and D2 components with the relative magnitude of each com...
متن کاملThe midbrain dopaminergic system: anatomy and genetic variation in dopamine neuron number of inbred mouse strains.
The mesotelencephalic dopamine system is genetically variable and affects motor behavior, motivation, and learning. Here we examine the genetic variation of mesencephalic DA neuron number in a quasi-congenic RQI mouse strain and its background partner and in a recombinant inbred strain with different levels of mesencephalic tyrosine hydroxylase activity (TH/MES). We used B6.Cb4i5-alpha6/Vad, C5...
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ژورنال
عنوان ژورنال: Scholarpedia
سال: 2007
ISSN: 1941-6016
DOI: 10.4249/scholarpedia.3737